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1

Sodium-Coupled Transport of the Short Chain Fatty Acid Butyrate by SLC5A8 and Its Relevance to Colon Cancer

Muthusamy Thangaraju, Gail Cresci, Shiro Itagaki, John Mellinger, Darren D. Browning, Franklin G. Berger, Puttur D. Prasad, Vadivel Ganapathy

Journal:

Journal of Gastrointestinal Surgery

Year:

2008

Language:

english

File:

PDF, 428 KB

english, 2008

2

Cloning and Functional Expression of the Human Type 1 Sigma Receptor (hSigmaR1)

Ramesh Kekuda, Puttur D. Prasad, You-Jun Fei, Frederick H. Leibach, Vadivel Ganapathy

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 169 KB

english, 1996

3

OCTN2-targeted nanoparticles for oral delivery of paclitaxel: differential impact of the polyethylene glycol linker size on drug delivery in vitro , in situ , and in vivo

Kou, Longfa, Sun, Rui, Xiao, Shuyi, Cui, Xiao, Sun, Jin, Ganapathy, Vadivel, Yao, Qing, Chen, Ruijie

Journal:

Year:

2020

Language:

english

File:

PDF, 2.69 MB

english, 2020

4

Citrate transport and metabolism in mammalian cells : Prostate epithelial cells and prostate cancer

Maria E. Mycielska, Ameet Patel, Nahit Rizaner, Maciej P. Mazurek, Hector Keun, Anup Patel, Vadivel Ganapathy, Mustafa B. A. Djamgoz

Journal:

Year:

2009

Language:

english

File:

PDF, 348 KB

english, 2009

5

Regulatory mechanisms of SNAT2, an amino acid transporter, in L6 rat skeletal muscle cells by insulin, osmotic shock and amino acid deprivation

Hitoshi Kashiwagi, Kojiro Yamazaki, Yoh Takekuma, Vadivel Ganapathy, Mitsuru Sugawara

Journal:

Year:

2009

Language:

english

File:

PDF, 443 KB

english, 2009

6

Electrogenic Nature of Rat Sodium-Dependent Multivitamin Transport

Puttur D. Prasad, Sonne R. Srinivas, Haiping Wang, Frederick H. Leibach, Lawrence D. Devoe, Vadivel Ganapathy

Journal:

Biochemical and Biophysical Research Communications

Year:

2000

Language:

english

File:

PDF, 62 KB

english, 2000

7

Analysis of sigma receptor (σR1) expression in retinal ganglion cells cultured under hyperglycemic conditions and in diabetic mice

M Shamsul Ola, Pamela Moore, Dennis Maddox, Amira El-Sherbeny, Wei Huang, Penny Roon, Neeraj Agarwal, Vadivel Ganapathy, Sylvia B Smith

Journal:

Molecular Brain Research

Year:

2002

Language:

english

File:

PDF, 644 KB

english, 2002

8

Human Na+-coupled citrate transporter: primary structure, genomic organization, and transport function

Katsuhisa Inoue, Lina Zhuang, Vadivel Ganapathy

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 238 KB

english, 2002

9

Sodium-coupled vitamin C transporter (SVCT2): expression, function, and regulation in intervertebral disc cells

Chothe, Paresh P., Chutkan, Norman, Sangani, Rajnikumar, Wenger, Karl H., Prasad, Puttur D., Thangaraju, Muthusamy, Hamrick, Mark W., Isales, Carlos M., Ganapathy, Vadivel, Fulzele, Sadanand

Journal:

The Spine Journal

Year:

2013

Language:

english

File:

PDF, 1.21 MB

english, 2013

10

Sodium- and chloride-dependent, cocaine-sensitive, high-affinity binding of nisoxetine to the human placental norepinephrine transporter

Jayanthi, Lankupalle D., Prasad, Puttur D., Ramamoorthy, Sammanda, Mahesh, Virendra B., Leibach, Frederick H., Ganapathy, Vadivel

Journal:

Year:

1993

Language:

english

File:

PDF, 1.03 MB

english, 1993

11

Peptide Transporters in the Intestine and the Kidney

Leibach, Frederick H., Ganapathy, Vadivel

Journal:

Annual Review of Nutrition

Year:

1996

Language:

english

File:

PDF, 1.35 MB

english, 1996

12

Comparative analysis of sodium coupled vitamin C transporter 2 in human osteoarthritis grade 1 and grade 3 tissues

Blackburn, Alan R, Hamrick, Mark W, Chutkan, Norman, Sangani, Rajnikumar, Waller, Jennifer L, Corpe, Raymond, Prasad, Puttur D, Isales, Carlos M, Ganapathy, Vadivel, Fulzele, Sadanand

Journal:

BMC Musculoskeletal Disorders

Year:

2014

Language:

english

File:

PDF, 931 KB

english, 2014

13

Human sodium-coupled citrate transporter, the orthologue of Drosophila Indy, as a novel target for lithium action

INOUE, Katsuhisa, ZHUANG, Lina, MADDOX, Dennis M., SMITH, Sylvia B., GANAPATHY, Vadivel

Journal:

Biochemical Journal

Year:

2003

Language:

english

File:

PDF, 148 KB

english, 2003

14

Gut Microbiome and Colon Cancer: Role of Bacterial Metabolites and Their Molecular Targets in the Host

Bhutia, Yangzom D., Ogura, Jiro, Sivaprakasam, Sathish, Ganapathy, Vadivel

Journal:

Current Colorectal Cancer Reports

Year:

2017

Language:

english

File:

PDF, 333 KB

english, 2017

15

Recent advances in drug delivery via the organic cation/carnitine transporter 2 (OCTN2/SLC22A5)

Kou, Longfa, Sun, Rui, Ganapathy, Vadivel, Yao, Qing, Chen, Ruijie

Journal:

Expert Opinion on Therapeutic Targets

Year:

2018

Language:

english

File:

PDF, 2.06 MB

english, 2018

16

Endocytosis of ATB 0,+ (SLC6A14)-targeted liposomes for drug delivery and its therapeutic application for pancreatic cancer

Kou, Longfa, Huang, Huirong, Lin, Xinlu, Jiang, Xinyu, Bao, Shihui, Luo, Qiuhua, Sun, Jin, Yao, Qing, Ganapathy, Vadivel, Chen, Ruijie

Journal:

Expert Opinion on Drug Delivery

Year:

2020

Language:

english

File:

PDF, 3.79 MB

english, 2020

17

Transport of valganciclovir, a ganciclovir prodrug, via peptide transporters PEPT1 and PEPT2

Mitsuru Sugawara, Wei Huang, You-Jun Fei, Frederick H. Leibach, Vadivel Ganapathy, Malliga E. Ganapathy

Journal:

Journal of Pharmaceutical Sciences

Year:

2000

Language:

english

File:

PDF, 231 KB

english, 2000

18

Expression of cyclic guanosine monophosphate-dependent protein kinase in metastatic colon carcinoma cells blocks tumor angiogenesis

In-Kiu Kwon, Patricia V. Schoenlein, Jennifer Delk, Kebin Liu, Muthusmy Thangaraju, Nickolai O. Dulin, Vadivel Ganapathy, Franklin G. Berger, Darren D. Browning

Journal:

Year:

2008

Language:

english

File:

PDF, 356 KB

english, 2008

19

Transport by SLC5A8 with subsequent inhibition of histone deacetylase 1 (HDAC1) and HDAC3 underlies the antitumor activity of 3-bromopyruvate

Muthusamy Thangaraju, Senthil K. Karunakaran, Shiro Itagaki, Elangovan Gopal, Selvakumar Elangovan, Puttur D. Prasad, Vadivel Ganapathy

Journal:

Year:

2009

Language:

english

File:

PDF, 579 KB

english, 2009

20

Regulation of proton-coupled folate transporter in retinal Müller cells by the antipsoriatic drug monomethylfumarate

B. Renee Bozard, Paresh P. Chothe, Amany Tawfik, Cory Williams, Sadanand Fulzele, Puttur D. Prasad, Pamela M. Martin, Vadivel Ganapathy, Sylvia B. Smith

Journal:

Year:

2012

Language:

english

File:

PDF, 1.40 MB

english, 2012

21

Expression and function of iron-regulatory proteins in retina

Jaya P. Gnana-Prakasam, Pamela M. Martin, Sylvia B. Smith, Vadivel Ganapathy

Journal:

Year:

2010

Language:

english

File:

PDF, 158 KB

english, 2010

22

Human Serotonin Transporter: Regulation by the Neuroprotective Agent Aurintricarboxylic Acid and by Epidermal Growth Factor

Ramesh Kekuda, Viviana Torres-Zamorano, Frederick H. Leibach, Vadivel Ganapathy

Journal:

Journal of Neurochemistry

Year:

1997

Language:

english

File:

PDF, 798 KB

english, 1997

23

Exon-Intron Structure, Analysis of Promoter Region, and Chromosomal Localization of the Human Type 1 σ Receptor Gene

Puttur D. Prasad, Hui W. Li, You-Jun Fei, Malliga E. Ganapathy, Takuya Fujita, Lisa H. Plumley, Teresa L. Yang-Feng, Frederick H. Leibach, Vadivel Ganapathy

Journal:

Journal of Neurochemistry

Year:

1998

Language:

english

File:

PDF, 1.30 MB

english, 1998

24

Cloning and Functional Characterization of a σ Receptor from Rat Brain

Pankaj Seth, You-Jun Fei, Hui W. Li, Wei Huang, Frederick H. Leibach, Vadivel Ganapathy

Journal:

Journal of Neurochemistry

Year:

1998

Language:

english

File:

PDF, 1.08 MB

english, 1998

25

Functional Expression of the Serotonin Transporter in Immortalized Rat Brain Microvessel Endothelial Cells

Peter Brust, Anne Friedrich, Istvan A. Krizbai, Ralf Bergmann, Françoise Roux, Vadivel Ganapathy, Bernd Johannsen

Journal:

Journal of Neurochemistry

Year:

2000

Language:

english

File:

PDF, 153 KB

english, 2000

26

Keratinocytes Join Forces with Immune Cells in the Prosecution of SMVT as a “False” Biotin Transporter

Prasad, Puttur D, Ganapathy, Vadivel

Journal:

The Journal of Investigative Dermatology

Year:

2003

Language:

english

File:

PDF, 55 KB

english, 2003

27

Reduced-folate carrier (RFC) is expressed in placenta and yolk sac, as well as in cells of the developing forebrain, hindbrain, neural tube, craniofacial region, eye, limb buds and heart

Dennis M Maddox, Anna Manlapat, Penny Roon, Puttur Prasad, Vadivel Ganapathy, Sylvia B Smith

Journal:

BMC Developmental Biology

Year:

2003

Language:

english

File:

PDF, 1.77 MB

english, 2003

28

Localization of peptide transporter in nuclei and lysosomes of the pancreas

Dale E. Bockman, Vadivel Ganapathy, Thomas G. Oblak, Frederick H. Leibach

Journal:

Journal of Gastrointestinal Cancer

Year:

1997

Language:

english

File:

PDF, 944 KB

english, 1997

29

SLC19: the folate/thiamine transporter family

Vadivel Ganapathy, SylviaB. Smith, PutturD. Prasad

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2004

Language:

english

File:

PDF, 217 KB

english, 2004

30

Effects of hyperglycemia and oxidative stress on the glutamate transporters GLAST and system xc−in mouse retinal Müller glial cells

Barbara Mysona, Ying Dun, Jennifer Duplantier, Vadivel Ganapathy, Sylvia B. Smith

Journal:

Cell and Tissue Research

Year:

2009

Language:

english

File:

PDF, 422 KB

english, 2009

31

Interaction of Ibuprofen and Other Structurally Related NSAIDs with the Sodium-Coupled Monocarboxylate Transporter SMCT1 (SLC5A8)

Shirou Itagaki, Elangovan Gopal, Lina Zhuang, You-Jun Fei, Seiji Miyauchi, Puttur D. Prasad, Vadivel Ganapathy

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 391 KB

english, 2006

32

Transport of Nicotinate and Structurally Related Compounds by Human SMCT1 (SLC5A8) and Its Relevance to Drug Transport in the Mammalian Intestinal Tract

Elangovan Gopal, Seiji Miyauchi, Pamela M. Martin, Sudha Ananth, Penny Roon, Sylvia B. Smith, Vadivel Ganapathy

Journal:

Pharmaceutical Research

Year:

2007

Language:

english

File:

PDF, 521 KB

english, 2007

33

Functional Identification of a Novel Transport System for Endogenous and Synthetic Opioid Peptides in the Rabbit Conjunctival Epithelial Cell Line CJVE

Sudha Ananth, Senthil Karunakaran, Pamela M. Martin, Chandrasekharam N. Nagineni, John J. Hooks, Sylvia B. Smith, Puttur D. Prasad, Vadivel Ganapathy

Journal:

Pharmaceutical Research

Year:

2009

Language:

english

File:

PDF, 266 KB

english, 2009

34

Colonic Gene Expression in Conventional and Germ-Free Mice with a Focus on the Butyrate Receptor GPR109A and the Butyrate Transporter SLC5A8

Gail A. Cresci, Muthusamy Thangaraju, John D. Mellinger, Kebin Liu, Vadivel Ganapathy

Journal:

Journal of Gastrointestinal Surgery

Year:

2010

Language:

english

File:

PDF, 641 KB

english, 2010

35

Rapid Report : Na+- and Cl−-coupled active transport of carnitine by the amino acid transporter ATB0,+ from mouse colon expressed in HRPE cells and Xenopus oocytes

Takeo Nakanishi, Takahiro Hatanaka, Wei Huang, Puttur D. Prasad, Frederick H. Leibach, Malliga E. Ganapathy, Vadivel Ganapathy

Journal:

The Journal of Physiology

Year:

2001

Language:

english

File:

PDF, 545 KB

english, 2001

36

Transport characteristics of N-acetyl-l-aspartate in rat astrocytes: involvement of sodium-coupled high-affinity carboxylate transporter NaC3/NaDC3-mediated transport system

Takuya Fujita, Hiromi Katsukawa, Etsuo Yodoya, Miyuki Wada, Ayumi Shimada, Naoki Okada, Akira Yamamoto, Vadivel Ganapathy

Journal:

Journal of Neurochemistry

Year:

2005

Language:

english

File:

PDF, 205 KB

english, 2005

37

Identity of SMCT1 (SLC5A8) as a neuron-specific Na+-coupled transporter for active uptake of l-lactate and ketone bodies in the brain

Pamela M. Martin, Elangovan Gopal, Sudha Ananth, Lina Zhuang, Shiro Itagaki, Balakrishna M. Prasad, Sylvia B. Smith, Puttur D. Prasad, Vadivel Ganapathy

Journal:

Journal of Neurochemistry

Year:

2006

Language:

english

File:

PDF, 542 KB

english, 2006

38

Serine racemase expression and d-serine content are developmentally regulated in neuronal ganglion cells of the retina

Ying Dun, Jennifer Duplantier, Penny Roon, Pamela M. Martin, Vadivel Ganapathy, Sylvia B. Smith

Journal:

Journal of Neurochemistry

Year:

2008

Language:

english

File:

PDF, 595 KB

english, 2008

39

The blood–brain barrier transport and cerebral distribution of guanidinoacetate in rats: involvement of creatine and taurine transporters

Masanori Tachikawa, Yasuyuki Kasai, Reiji Yokoyama, Jun Fujinawa, Vadivel Ganapathy, Tetsuya Terasaki, Ken-ichi Hosoya

Journal:

Journal of Neurochemistry

Year:

2009

Language:

english

File:

PDF, 331 KB

english, 2009

40

Improvement of L-dopa absorption by dipeptidyl derivation, utilizing peptide transporter PepT1

Ikumi Tamai, Takeo Nakanishi, Haruki Nakahara, Yoshimich Sai, Vadivel Ganapathy, Frederick H. Leibach, Akira Tsuji

Journal:

Journal of Pharmaceutical Sciences

Year:

1998

Language:

english

File:

PDF, 74 KB

english, 1998

41

Expression cloning of a mammalian proton-coupled oligopeptide transporter

Fei, You-Jun, Kanai, Yoshikatsu, Nussberger, Stephan, Ganapathy, Vadivel, Leibach, Frederick H., Romero, Michael F., Singh, Satish K., Boron, Walter F., Hediger, Matthias A.

Journal:

Year:

1994

File:

PDF, 664 KB

1994

42

Molecular origin of plasma membrane citrate transporter in human prostate epithelial cells

Mazurek, Maciej P, Prasad, Puttur D, Gopal, Elangovan, Fraser, Scott P, Bolt, Leszek, Rizaner, Nahit, Palmer, Christopher P, Foster, Christopher S, Palmieri, Ferdinando, Ganapathy, Vadivel

Journal:

Year:

2010

Language:

english

File:

PDF, 1010 KB

english, 2010

43

Substrate specificity and functional characterisation of the H+/amino acid transporter rat PAT2 (Slc36a2)

David J Kennedy, Kelly M Gatfield, John P Winpenny, Vadivel Ganapathy, David T Thwaites

Journal:

British Journal of Pharmacology

Year:

2005

Language:

english

File:

PDF, 279 KB

english, 2005

44

Structure, function and immunolocalization of a proton-coupled amino acid transporter (hPAT1) in the human intestinal cell line Caco-2

Zhong Chen, You-Jun Fei, Catriona M. H. Anderson, Katherine A. Wake, Seiji Miyauchi, Wei Huang, David T. Thwaites, Vadivel Ganapathy

Journal:

The Journal of Physiology

Year:

2003

Language:

english

File:

PDF, 531 KB

english, 2003

45

Down-regulation of placental transport of amino acids precedes the development of intrauterine growth restriction in rats fed a low protein diet

Nina Jansson, Jessica Pettersson, Allah Haafiz, Anette Ericsson, Isabelle Palmberg, Mattias Tranberg, Vadivel Ganapathy, Theresa L. Powell, Thomas Jansson

Journal:

The Journal of Physiology

Year:

2006

Language:

english

File:

PDF, 387 KB

english, 2006

46

Human solute carrier SLC6A14 is the β-alanine carrier

Catriona M. H. Anderson, Vadivel Ganapathy, David T. Thwaites

Journal:

The Journal of Physiology

Year:

2008

Language:

english

File:

PDF, 331 KB

english, 2008

47

Taurine uptake across the human intestinal brush-border membrane is via two transporters: H+-coupled PAT1 (SLC36A1) and Na+- and Cl−-dependent TauT (SLC6A6)

Catriona M. H. Anderson, Alison Howard, Julian R. F. Walters, Vadivel Ganapathy, David T. Thwaites

Journal:

The Journal of Physiology

Year:

2009

Language:

english

File:

PDF, 430 KB

english, 2009

48

Targeting the Sodium-Dependent Multivitamin Transporter (SMVT) for Improving the Oral Absorption Properties of a Retro-Inverso Tat Nonapeptide

Srinivasan Ramanathan, Shahriar Pooyan, Stanley Stein, Puttur D. Prasad, Jihong Wang, Michael J. Leibowitz, Vadivel Ganapathy, Patrick J. Sinko

Journal:

Pharmaceutical Research

Year:

2001

Language:

english

File:

PDF, 185 KB

english, 2001

49

A Comparison of Caveolae and Caveolin-1 to Folate Receptor α in Retina and Retinal Pigment Epithelium

Christy C. Bridges, Amira El-Sherbeny, Penny Roon, M. Shamsul Ola, Ramesh Kekuda, Vadivel Ganapathy, Richard S. Cameron, Patricia L. Cameron, Sylvia B. Smith

Journal:

Journal of Molecular Histology

Year:

2001

Language:

english

File:

PDF, 1.86 MB

english, 2001

50

Transport of Amino Acid Esters and the Amino-Acid-Based Prodrug Valganciclovir by the Amino Acid Transporter ATB0,+

Nagavedi S. Umapathy, Vadivel Ganapathy, Malliga E. Ganapathy

Journal:

Pharmaceutical Research

Year:

2004

Language:

english

File:

PDF, 150 KB

english, 2004